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Advancing Science & Promoting Understanding of Traumatic Stress

THIS MONTH'S FEATURE: MEDICATION FOR PTSD

Medications are often used to treat PTSD. Effective Treatment for PTSD includes therapy, medication, or a combination of therapy and drugs. New medications are better at relieving PTSD symptoms than some drugs prescribed in the past.

The only two FDA approved medications for PTSD are sertraline (Zoloft) and paroxetine (Paxil). Other medications are sometimes used for specific symptoms of PTSD, like sleep problems and nightmares. Prescription drugs can not eliminate PTSD completely, but they can reduce the symptoms. However, some drugs that may help in the short run can also prevent recovery or even prove harmful.

Effective medications : The drugs sertraline (Zoloft) and paroxetine (Paxil) can reduce symptoms of PTSD. Both are called SSRI’s or Selective Serotonin Reuptake Inhibitors. SSRI’s have been extensively tested. They work by regulating brain chemistry. For example, with depression, you may not have enough of a chemical called serotonin. SSRIs raise the level of serotonin in your brain to relieve symptoms. Other medications are effective for reducing symptoms of PTSD. Talk to your doctor about which medications are right for you. 

Beware of medications for sleep and nightmares

Sleep and anti-anxiety medications can create the same problems as using alcohol and drugs to self-treat symptoms. These medications might help in the short term, but can have long term costs, such as serious addiction problems, misuse, and other medical issues.

Abuse of prescription medications, like abuse of drugs, is a problem that can occur. Benzodiazepines (for example, Valium, Xanax, or Klonopin) can be particularly problematic because they are prone to physical dependence. Other drugs like atypical antipsychotics such as quetiapine (Seroquel) also should be used with caution for side effect reasons. Importantly, benzodiazepines also may limit the effectiveness of talk therapy, which helps PTSD.

Non-drug therapies for PTSD : Medications can provide relief from PTSD symptoms. However, Prolonged Exposure therapy (PE) and Cognitive Processing Therapy CPT) work better than medications alone in reducing PTSD symptoms. These therapies, among others, are best for effective treatment for PTSD and may be combined with the use of medications. Talk to your doctor about which therapies are right for you.

 

 
CLINICIAN'S TRAUMA UPDATE-Online  Issue 4(5), October 2010 . For COMPLETE summaries, see this month's CTU online pdf  >>read

This issue of CTU-Online contains 8 summaries:

A guide to guidelines on PTSD treatment ; Prolonged exposure outperformsnon-specific therapy, but not other active treatments ; Intensive CBT for PTSD offers faster benefit ; Unexpected findings on imagery rehearsel for Veterans with PTSD ; Support for phase-based treatment of chronic PTSD ; African- American women have problems completing PTSD treatments ; Telemental health and the group therapy process ; Greater risk in developing dementia in Veterans of PTSD